FKBP2 — FKBP prolyl isomerase 2
FKBP2 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FKBP2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Cytotoxic effector Cytotoxicity | ADAM23, CTSW, EMP3, IFITM2, IGFBP3, KLRG1, LYAR, PLP2 +11 more | View in SCUBA |
| Goblet cells | ER Chaperone Glycosylation Protein processing & ER | ANG, ATP6V1G1, CD63, NANS, OST4, PPIC, RABAC1, REEP5 +4 more | View in SCUBA |
| Innate lymphoid cells | NF-κB Inflammatory Activation Inflammation | AHI1, CD83, FAM107B, GADD45A, HES4, KDM6B, MRPS36, PRPF4B +7 more | View in SCUBA |
| Macrophages | ER Protein Glycosylation Vesicular traficking | AK2, ALG3, ALG5, BABAM1, CKLF, CRELD2, DDOST, DPM3 +21 more | View in SCUBA |
| Natural Killer cells | mRNA Splicing RNA processing & translation | CHMP4A, DDX17, FAM107B, GOLGB1, HNRNPH1, LUC7L3, PNN, RSRC2 +1 more | View in SCUBA |
About the gene
| Synonyms | FKBP-13, FKBP13, PPIase |
|---|---|
| Chromosome | 11: 64241003-64244132 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Isomerase, Rotamase |
Function
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.