REEP5 — Receptor accessory protein 5
REEP5 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
REEP5's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | ER/vesicle trafficking Protein processing & ER | ATP6V0B, CD99, DIAPH1, HCST, M6PR, MTDH, MTPN, SCPEP1 +1 more | View in SCUBA |
| CD4⁺ T cells | Interferon response Anti-viral | ACTN4, CAPZA1, CHMP4A, CHMP5, EFHD2, IL12RB1, LSP1, PARP14 +7 more | View in SCUBA |
| CD8⁺ T cells | Autophagy Metabolic Stress Stress | CREM, CTSC, DNAJB6, DOK2, EFHD2, GNG2, ICOS, MAP1LC3B +2 more | View in SCUBA |
| Goblet cells | ER Chaperone Glycosylation Protein processing & ER | ANG, ATP6V1G1, CD63, FKBP2, NANS, OST4, PPIC, RABAC1 +4 more | View in SCUBA |
| Macrophages | ER Protein Processing Housekeeping | ACTR1A, ANXA7, ATP6AP1, ATP6AP2, ATP6V0B, ATP6V0E1, AUP1, BCAP31 +41 more | View in SCUBA |
About the gene
| Synonyms | C5orf18, D5S346, DP1, POB16, TB2, Yip2e |
|---|---|
| Chromosome | 5: 112876385-112922289 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
Function
Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.