SCUBA

RABAC1 — Rab acceptor 1

RABAC1 belongs to a gene co-expression module in 9 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

RABAC1's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsMHC-II antigen presentation
B cell maturation
CD53, CD81, CYTH1, DAPP1, DNAJC10, FAM3C, FCRLA, GPR18 +11 moreView in SCUBA
CD4⁺ T cellsCell motility/adhesion
migration & adhesion
ANXA2, CCDC107, CYBA, FAM50A, GLIPR2, GRAP2, GYG1, ITM2B +14 moreView in SCUBA
FibroblastsER Secretory Processing
Housekeeping
DAD1, ELOB, FKBP1A, MYL12B, POLR2L, PPIB, SPCS1, SSR4 +2 moreView in SCUBA
Gamma-delta T cellsActin-based Motility
Cytoskeletal
APBB1IP, CD58, COMMD7, CORO1B, CTSD, EVL, FDFT1, HMOX2 +13 more
Glial cellsGlutathione Detoxification
Stress
DAD1, GSTP1, ITM2B, MGST3, RHOC, SRP14, TMA7, VIM +1 moreView in SCUBA
Goblet cellsER Chaperone Glycosylation
Protein processing & ER
ANG, ATP6V1G1, CD63, FKBP2, NANS, OST4, PPIC, REEP5 +4 moreView in SCUBA
Lymphatic endothelialOxidative Stress Response
Stress
AP2S1, APRT, ATOX1, C4orf3, FKBP1A, GADD45GIP1, GSTP1, SH3BGRL3 +1 moreView in SCUBA
MacrophagesER Protein Processing
Housekeeping
ACTR1A, ANXA7, ATP6AP1, ATP6AP2, ATP6V0B, ATP6V0E1, AUP1, BCAP31 +41 moreView in SCUBA
Smooth muscle cellsEndolysosomal Trafficking
Housekeeping
ARPC3, CD164, FKBP1A, IFITM3, LAMTOR1, NDFIP1, RAB5C, TMEM50AView in SCUBA

About the gene

SynonymsPRA1, PRAF1, YIP3
Chromosome19: 41956681-41959321
Predicted locationMembrane
Essential geneNo
Protein classPredicted membrane proteins, Transporters

Function

General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.