HDGF — Heparin binding growth factor
HDGF belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
HDGF's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Cellular biosynthesis Housekeeping | CCDC32, CTSB, MEA1, MESD, MFSD6, MRPS11, MTHFD2, NAA60 +9 more | View in SCUBA |
| CD8⁺ T cells | S-phase Chromatin Replication Cell cycle | ANP32E, BRCA2, CKAP2, HP1BP3, LBR, MIS18BP1, NSD2, NUCKS1 +4 more | View in SCUBA |
| Endothelial | Nuclear Transport Housekeeping | AAMDC, ANP32B, CBX5, CDK4, CKAP4, COMMD4, COQ2, CSE1L +18 more | View in SCUBA |
| Gamma-delta T cells | snRNP Splicing RNA processing & translation | CHCHD2, DAZAP1, GAPDH, GIT1, GUK1, ILF2, LAMTOR5, MRPS15 +16 more | |
| Goblet cells | CCT Chaperonin Complex Protein processing & ER | CCT5, CCT6A, HNRNPA3, HNRNPC, IDH2, PTGES3, SMS, SRP9 +2 more | View in SCUBA |
About the gene
| Synonyms | HMG1L2 |
|---|---|
| Chromosome | 1: 156742109-156766925 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins |
| Molecular function | DNA-binding, Growth factor, Heparin-binding, Repressor |
| Biological process | Transcription, Transcription regulation |
Function
Acts as a transcriptional repressor. Has mitogenic activity for fibroblasts. Heparin-binding protein. Does not have mitogenic activity for fibroblasts. Does not bind heparin. Has mitogenic activity for fibroblasts. Heparin-binding protein
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.