NUCKS1 — Nuclear casein kinase and cyclin dependent kinase substrate 1
NUCKS1 belongs to a gene co-expression module in 13 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NUCKS1's module in each cell type
About the gene
| Synonyms | NUCKS |
|---|---|
| Chromosome | 1: 205712822-205750182 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Biological process | DNA damage, DNA repair |
Function
Chromatin-associated protein involved in DNA repair by promoting homologous recombination (HR). Binds double-stranded DNA (dsDNA) and secondary DNA structures, such as D- loop structures, but with less affinity than RAD51AP1
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.