HNRNPA3 — Heterogeneous nuclear ribonucleoprotein A3

HNRNPA3 belongs to a gene co-expression module in 12 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

HNRNPA3's module in each cell type

Cell type	Module	Shares the module with
CD4⁺ T cells	Actomyosin signaling migration & adhesion	ACIN1, CYBC1, EIF4G3, GALNT1, NCKAP1L, PPP1R12A, PRKCH, PTPRA +8 more	View in SCUBA
CD8⁺ T cells	Nuclear RNA Splicing RNA processing & translation	CBX3, DNAJC8, HNRNPD, HNRNPR, MAZ, PGP, PPIG, PSMD1 +5 more	View in SCUBA
Endothelial	mRNA Splicing RNA processing & translation	DIAPH1, EIF4A3, FUBP1, GLRX5, HNRNPA2B1, HNRNPD, KHDRBS1, MAGOH +8 more	View in SCUBA
Enterocytes	Nucleolar RNA-binding RNA processing & translation	HMGB1, HMGN2, HNRNPA1, HNRNPA2B1, HSP90AA1, HSP90AB1, NCL, NPM1 +2 more	View in SCUBA
Gamma-delta T cells	Post-transcriptional RNA Regulation RNA processing & translation	CCNG1, DHX15, FUBP1, IPO7, ITPR2, OSBPL3, PLEKHB2, SP140
Glial cells	AHR-Cytokine Activation Activation	AHR, BHLHE40, CAVIN1, CDH19, IL6ST, ITPR1, RBM39, SYNE1 +1 more	View in SCUBA
Goblet cells	CCT Chaperonin Complex Protein processing & ER	CCT5, CCT6A, HDGF, HNRNPC, IDH2, PTGES3, SMS, SRP9 +2 more	View in SCUBA
Innate lymphoid cells	RNA Processing & Proteostasis RNA processing & translation	BZW1, CBX5, CSNK1A1, DDX21, EIF2S1, EIF3J, ENPP1, FNBP1 +11 more	View in SCUBA
Macrophages	RNA Splicing Processing Housekeeping	ARMCX3, CIRBP, ELK4, GATAD1, H3-3B, HNRNPA2B1, HNRNPL, HP1BP3 +13 more	View in SCUBA
Natural Killer cells	hnRNP RNA Processing RNA processing & translation	CBX3, GNG5, HNRNPA2B1, HNRNPAB, RAN, SLC25A5, YWHAE	View in SCUBA
Neutrophils	RNA Splicing Housekeeping	ATF4, FUS, HNRNPA2B1, IRF2BP2, SFPQ, SRSF3, TRA2B
Smooth muscle cells	hnRNP & Proteasome RNA processing & translation	ARF1, CCT2, GDI2, HNRNPA2B1, HNRNPF, HNRNPU, PSMD8, PSMG2 +2 more	View in SCUBA

About the gene

Synonyms	HNRPA3
Chromosome	2: 177212694-177223959
Predicted location	Intracellular
Essential gene	No
Protein class	Plasma proteins, Predicted intracellular proteins
Molecular function	Ribonucleoprotein, RNA-binding
Biological process	mRNA processing, mRNA splicing

Function

Plays a role in cytoplasmic trafficking of RNA. Binds to the cis-acting response element, A2RE. May be involved in pre-mRNA splicing

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.