MIS18BP1 — MIS18 binding protein 1
MIS18BP1 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MIS18BP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Rho-GTPase Migration migration & adhesion | ARHGAP18, ARHGEF7, FNBP1, HELZ, LPXN, MAP4K1, PREX1, RORA +4 more | View in SCUBA |
| CD8⁺ T cells | S-phase Chromatin Replication Cell cycle | ANP32E, BRCA2, CKAP2, HDGF, HP1BP3, LBR, NSD2, NUCKS1 +4 more | View in SCUBA |
| Goblet cells | S/G2 Preparation Cell cycle | DTYMK, EXOSC8, HMGN2, LMNB1, LSM3, LSM5, MIS18A, SMC2 +4 more | View in SCUBA |
| Monocytes | Glucocorticoid Response Tissue adaptation | FKBP5, FMN1, NUDT16, SAP30, SMAP2, SPTLC2, SULT1A1, TSC22D3 +2 more | View in SCUBA |
| Neutrophils | S-G2-M Cell Cycle Cell cycle | ATAD2, CENPP, CNTRL, EZH2, LNPEP, RRM2, SMC4, TOPBP1 +1 more |
About the gene
| Synonyms | C14orf106, FLJ11186, KIAA1903, KNL2, M18BP1 |
|---|---|
| Chromosome | 14: 45203190-45253540 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Molecular function | DNA-binding |
| Biological process | Cell cycle, Cell division, Mitosis |
Function
Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.