KRT20 — Keratin 20
KRT20 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
KRT20's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Surface colonocyte differentiation Epithelial development | AGR3, ATP1B1, BMP3, CLDN3, DSP, KLF5, NEURL1B, PDLIM1 +2 more | View in SCUBA |
| Goblet cells | Inflammatory goblet response Immune function | ANXA1, B4GALT1, CAPN8, CEACAM6, DST, LYPD8, MUC13, MXD1 +8 more | View in SCUBA |
About the gene
| Synonyms | CK20, K20, MGC35423 |
|---|---|
| Chromosome | 17: 40875889-40885242 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Biological process | Apoptosis |
Function
Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.