KLF5 — KLF transcription factor 5
KLF5 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
KLF5's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Hypoxia metabolic stress Stress | ARG2, ARL4D, AXIN2, BNIP3, CITED4, CNKSR2, GCA, GSTM3 +13 more | View in SCUBA |
| Enterocytes | Surface colonocyte differentiation Epithelial development | AGR3, ATP1B1, BMP3, CLDN3, DSP, KRT20, NEURL1B, PDLIM1 +2 more | View in SCUBA |
| Goblet cells | Colonocyte Differentiation Program Epithelial development | ASCL2, CAMK1D, CDK6, EDIL3, ENTPD5, FOXN3, HMGCS2, IRF2BP2 +8 more | View in SCUBA |
About the gene
| Synonyms | BTEB2, CKLF, IKLF |
|---|---|
| Chromosome | 13: 73054976-73077541 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Predicted intracellular proteins, Transcription factors |
| Molecular function | Activator, DNA-binding |
| Biological process | Transcription, Transcription regulation |
Function
Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.