NEURL1B — Neuralized E3 ubiquitin protein ligase 1B
NEURL1B belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NEURL1B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Wnt Angiogenic Remodeling ECM remodeling | ADAMTS4, ADGRL2, BAZ1A, FKBP11, IL4R, LDLRAD3, LEF1, MTHFD2 +5 more | View in SCUBA |
| Enterocytes | Surface colonocyte differentiation Epithelial development | AGR3, ATP1B1, BMP3, CLDN3, DSP, KLF5, KRT20, PDLIM1 +2 more | View in SCUBA |
About the gene
| Synonyms | DKFZP761M1511, Neur2, RNF67B |
|---|---|
| Chromosome | 5: 172641263-172691540 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Transferase |
| Biological process | Notch signaling pathway, Ubl conjugation pathway |
Function
E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.