PDIA4 — Protein disulfide isomerase family A member 4
PDIA4 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PDIA4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | UPR / ER Stress Protein processing & ER | CALR, CANX, CTSB, CTTN, GRN, HDLBP, HSP90B1, HSPA5 +10 more | View in SCUBA |
| Enterocytes | ER chaperone/UPR Protein processing & ER | ANXA2, CALR, EFNB2, ENO1, HSP90B1, HSPA5, MARCKS, ME1 +3 more | View in SCUBA |
| Gamma-delta T cells | ER Glycoprotein Quality Control Protein processing & ER | APOL2, BAG6, CALR, ELP3, GBP1, GBP2, GBP4, HEXB +9 more | |
| Goblet cells | UPR Chaperone Response Stress | CALR, CRELD2, GMPPB, LRRC59, MANF, NUCB2, P4HB, PDIA3 +2 more | View in SCUBA |
| Innate lymphoid cells | Mitochondrial Metabolic Housekeeping Mitochondrial & OxPhos | ALKBH7, ATF6B, BCAS1, COQ8A, DDT, DNAJC4, DPM3, EIF3M +16 more | View in SCUBA |
| Macrophages | ER Stress UPR Stress | ANKRD9, APEH, ARMCX6, BET1L, CALR, CCDC107, COPS2, DNAJB11 +20 more | View in SCUBA |
| Mucosal-associated invariant T cell | Cellular Housekeeping Housekeeping | AKR7A2, ANP32A, ANXA5, AP1M1, APEX1, APOBEC3C, CDC26, DBNL +17 more |
About the gene
| Synonyms | ERP70, ERP72 |
|---|---|
| Chromosome | 7: 149003062-149028662 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Isomerase |
| Biological process | Host-virus interaction |
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.