PPP6R3 — Protein phosphatase 6 regulatory subunit 3
PPP6R3 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PPP6R3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | DNA Damage Response DNA/chromatin regulation | AP1B1, CCAR1, CHD8, DOCK2, EP400, ERBIN, GOLM2, IPO8 +17 more | |
| Lymphatic endothelial | Actin-based Migration Cytoskeletal | AUTS2, GAS7, MGAT5, NHSL1, PAN3, PCCA, TRIO, ZFPM2 | View in SCUBA |
| Macrophages | Rho GTPase Signaling Cytoskeletal | ABCC1, ABR, ANKRD17, ARFGEF2, ARHGAP10, ARID2, ATAD2B, ATP9B +44 more | View in SCUBA |
| Mucosal-associated invariant T cell | Cellular Maintenance Housekeeping | DCTN4, FAM13B, GBF1, GOLGA4, GPRIN3, HUWE1, ITSN2, PAFAH1B1 +4 more |
About the gene
| Synonyms | C11orf23, DKFZp781E17107, DKFZp781E2374, DKFZp781O2362, FLJ11058, FLJ43065, KIAA1558, MGC125711, MGC125712, PP6R3, SAP190, SAPL, SAPLa, SAPS3 |
|---|---|
| Chromosome | 11: 68460731-68615334 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. May have an important role in maintaining immune self-tolerance.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.