SDR16C5 — Short chain dehydrogenase/reductase family 16C member 5
SDR16C5 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SDR16C5's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Myeloid Contamination Cell contamination | BASP1, C7, CARMIL1, CCL23, CH25H, CSRP2, CTSC, DENND2D +20 more | View in SCUBA |
| Goblet cells | Inflammatory goblet response Immune function | ANXA1, B4GALT1, CAPN8, CEACAM6, DST, KRT20, LYPD8, MUC13 +8 more | View in SCUBA |
About the gene
| Synonyms | EPHD-2, RDH-E2, RDHE2 |
|---|---|
| Chromosome | 8: 56300005-56320776 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted membrane proteins |
| Molecular function | Oxidoreductase |
Function
Oxidoreductase with strong preference for NAD. Active in both the oxidative and reductive directions. Oxidizes all-trans-retinol in all-trans- retinaldehyde. No activity was detected with 11-cis- retinol or 11-cis-retinaldehyde as substrates with either NAD(+)/NADH or NADP(+)/NADPH
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.