MRPS34 — Mitochondrial ribosomal protein S34

MRPS34 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

MRPS34's module in each cell type

Cell type	Module	Shares the module with
CD19⁺ B cells	Mitochondrial Translation Mitochondrial & OxPhos	BOLA3, MRPL20, MRPL36, PDCD5, POLR2I, PSMA3, PSMB5, RPL26L1 +2 more	View in SCUBA
CD4⁺ T cells	Mitochondrial OxPhos Mitochondrial & OxPhos	AP2M1, ATP5MF, ATP6V0B, AURKAIP1, BSG, CALM3, CLTB, CSNK2B +19 more	View in SCUBA
Gamma-delta T cells	Mitoribosome Small Subunit Mitochondrial & OxPhos	ACADM, C14orf119, CHCHD1, COA3, COA4, COMMD8, GALK1, GEMIN6 +24 more
Hematopoietic progenitor cells	Proteostasis & OxPhos Mitochondrial & OxPhos	COX5A, EIF5A, HNRNPF, HSPA8, ILF2, NDUFB6, PSMB5, SLBP
Innate lymphoid cells	Mitochondrial Metabolism Mitochondrial & OxPhos	ACTR10, ANP32A, APOL3, ATP6V1E1, ECHS1, ERCC1, ETFB, GLRX3 +12 more	View in SCUBA
Macrophages	Complex I / NADH Dehydrogenase Mitochondrial & OxPhos	AHCY, ANP32A, ANTKMT, APEX1, ARL2, ATIC, ATP5F1A, ATP5ME +31 more	View in SCUBA
Mucosal-associated invariant T cell	Mitochondrial Ribosome Mitochondrial & OxPhos	AGTRAP, BRK1, C11orf68, C14orf119, CNPY2, CZIB, DCTPP1, DYNC1I2 +22 more

About the gene

Synonyms	MGC2616, MRP-S12
Chromosome	16: 1771890-1773150
Predicted location	Intracellular
Essential gene	Yes
Protein class	Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins
Molecular function	Ribonucleoprotein, Ribosomal protein

Function

Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for mitoribosome formation

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.