EIF4H — Eukaryotic translation initiation factor 4H
EIF4H belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
EIF4H's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Transcription-RNA Coupling DNA/chromatin regulation | AKNA, AP1G1, BTAF1, BZW1, CRNKL1, DDX6, DNTTIP2, DYNC1H1 +26 more | |
| Innate lymphoid cells | RNA Processing Mixed RNA processing & translation | AUP1, B3GAT3, CFDP1, CMTM3, DENR, FBXW5, FUCA1, FYTTD1 +13 more | View in SCUBA |
| Macrophages | RNA Processing Regulation Housekeeping | ACBD3, AQR, ARCN1, BFAR, BNIP3L, CCNI, CCNK, DIS3 +15 more | View in SCUBA |
| Mucosal-associated invariant T cell | NF-κB RNA Regulation RNA processing & translation | ARIH2, ATP1A1, BCLAF1, BNIP2, CALR, COG3, DDX6, EIF4G2 +14 more |
About the gene
| Synonyms | KIAA0038, WBSCR1, WSCR1 |
|---|---|
| Chromosome | 7: 74174231-74197122 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Initiation factor, RNA-binding |
| Biological process | Host-virus interaction, Protein biosynthesis |
Function
Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.