H4C3 — H4 clustered histone 3
H4C3 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
H4C3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Innate lymphoid cells | Septin Cytoskeleton Cytoskeleton & motility | ATP6V0C, C17orf49, CIAO2A, COX16, DARS1, DDOST, GET3, H2AC6 +18 more | View in SCUBA |
| Macrophages | Mitotic Chromosome Condensation Cell cycle | CKS1B, DTYMK, H2AX, HMGB2, KIF22, NCAPD2, RACGAP1, SAC3D1 +4 more | View in SCUBA |
| Monocytes | Histone Chromatin Remodeling Housekeeping | CTSD, H1-10, H1-2, H1-3, H1-4, H2AJ, HMGB2, HOXA9 | View in SCUBA |
| Mucosal-associated invariant T cell | Mitochondrial OxPhos Mitochondrial & OxPhos | ATP5MF, H2AZ1, INO80E, LYPLA2, NDUFA3, NDUFB1, SEM1, SGSM3 +3 more | |
| Natural Killer cells | Replication-Coupled Histones Cell cycle | H1-10, H1-2, H1-3, H1-4, H2AC6, H2AC8, H2BC15, H2BC4 | View in SCUBA |
| Neutrophils | Mitotic Spindle Cell cycle | ANP32B, ANP32E, DEK, H2AZ2, HMGB1, HNRNPH1, HP1BP3, NUCKS1 +4 more |
About the gene
| Synonyms | dJ221C16.1, H4/g, H4FG, HIST1H4C |
|---|---|
| Chromosome | 6: 26103933-26104337 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Predicted intracellular proteins |
| Molecular function | DNA-binding |
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.