SCUBA

NDUFB1 — NADH:ubiquinone oxidoreductase subunit B1

NDUFB1 belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

NDUFB1's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsOxPhos & redox
Mitochondrial & OxPhos
ATOX1, CHCHD2, HNRNPR, KIF5B, MRPS21, NDUFAB1, NDUFB2, POMP +5 moreView in SCUBA
EnterocytesMitochondrial Chaperonin
Mitochondrial & OxPhos
HINT1, HSPD1, HSPE1, MGST1, OST4, TMA7View in SCUBA
Gamma-delta T cellsChaperone Protein Folding
Protein processing & ER
AAMP, AHCYL1, CCT7, CCT8, CHMP5, COX17, DPY30, EIF2S2 +16 more
Goblet cellsElectron Transport Chain
Mitochondrial & OxPhos
ATP5IF1, ATP5ME, COX5B, DCXR, NDUFA2, NDUFA3, NDUFB10, NDUFB7 +5 moreView in SCUBA
Innate lymphoid cellsILC1 Cytoskeletal Metabolic
Cytoskeleton & motility
ATP5F1B, ATXN10, CCT7, CD82, DNPH1, GADD45GIP1, HMGA1, MEA1 +14 moreView in SCUBA
MacrophagesComplex I / NADH Dehydrogenase
Mitochondrial & OxPhos
AHCY, ANP32A, ANTKMT, APEX1, ARL2, ATIC, ATP5F1A, ATP5ME +31 moreView in SCUBA
Mucosal-associated invariant T cellMitochondrial OxPhos
Mitochondrial & OxPhos
ATP5MF, H2AZ1, H4C3, INO80E, LYPLA2, NDUFA3, SEM1, SGSM3 +3 more
Smooth muscle cellsRespiratory Chain Subunits
Mitochondrial & OxPhos
C19orf53, COX6A1, COX7B, MZT2B, PFN1, SNRPD2, SNX3, UBXN1 +2 moreView in SCUBA

About the gene

SynonymsCI-MNLL, MNLL
Chromosome14: 92116122-92121917
Predicted locationIntracellular, Membrane
Essential geneYes
Protein classEssential proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins
Biological processElectron transport, Respiratory chain, Transport

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.