NDUFA3 — NADH:ubiquinone oxidoreductase subunit A3

NDUFA3 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

NDUFA3's module in each cell type

Cell type	Module	Shares the module with
CD4⁺ T cells	Oxidative Phosphorylation Mitochondrial & OxPhos	AP2S1, ATP5F1C, ATP5PF, COPS9, COX6B1, EID1, FAM89B, FDPS +19 more	View in SCUBA
Gamma-delta T cells	Chaperone Protein Folding Protein processing & ER	AAMP, AHCYL1, CCT7, CCT8, CHMP5, COX17, DPY30, EIF2S2 +16 more
Goblet cells	Electron Transport Chain Mitochondrial & OxPhos	ATP5IF1, ATP5ME, COX5B, DCXR, NDUFA2, NDUFB1, NDUFB10, NDUFB7 +5 more	View in SCUBA
Innate lymphoid cells	Mitochondrial OxPhos Biogenesis Mitochondrial & OxPhos	AP1S1, ATOX1, ATP5ME, ATP5MF, C1QBP, CNIH1, CYC1, ERH +22 more	View in SCUBA
Macrophages	Inflammasome Oxidative Stress Inflammatory	ABI3, ADISSP, AKR1A1, ARHGDIB, ARPC1B, ASCL2, BLVRA, C1orf54 +33 more	View in SCUBA
Mucosal-associated invariant T cell	Mitochondrial OxPhos Mitochondrial & OxPhos	ATP5MF, H2AZ1, H4C3, INO80E, LYPLA2, NDUFB1, SEM1, SGSM3 +3 more

About the gene

Synonyms	B9
Chromosome	19: 54102728-54109257
Predicted location	Intracellular, Membrane
Essential gene	No
Protein class	Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins
Biological process	Electron transport, Respiratory chain, Transport

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.