C4ORF48 — Chromosome 4 open reading frame 48
C4ORF48 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
C4ORF48's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Cytoskeleton/motility migration & adhesion | ANXA2, ANXA4, BHLHE41, CAPG, CAPN2, CIB1, ISCU, LGALS1 +11 more | View in SCUBA |
| CD4⁺ T cells | Proteostasis OxPhos Housekeeping | AIP, ARPC1B, ATP6V1F, CHMP2A, IL2RG, NDUFA13, NDUFB10, PPP1R7 +6 more | View in SCUBA |
| Endothelial | Inflammatory EC Activation ECM remodeling | CAPG, CD200, COL6A1, COL6A2, IGFBP5, LAMP3, NT5E, OAF +4 more | View in SCUBA |
| Fibroblasts | Hypoxia Response Stress | ACSL4, AP2S1, ARFGAP3, EPAS1, HIF1A, IL4R, ISG20, NECTIN2 +8 more | View in SCUBA |
| Glial cells | Hyaluronan-CD44 Remodeling ECM remodeling | CBX3, CD44, HAS2, HES4, MIA, PLEKHA4, WWTR1 | View in SCUBA |
| Pericytes | Basement Membrane Remodeling ECM remodeling | ADA, CYBA, DKK3, EFEMP2, G0S2, ISG20, LAMB3, RCN3 +2 more | View in SCUBA |
| Smooth muscle cells | Basement Membrane Matrix ECM remodeling | ADH5, EFEMP2, FBXL7, MLXIP, MXRA8, PRNP, RTN4, VWA1 | View in SCUBA |
About the gene
| Chromosome | 4: 2041995-2043964 |
|---|---|
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Predicted secreted proteins |
| Molecular function | RNA-binding |
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.