PLEKHB2 — Pleckstrin homology domain containing B2
PLEKHB2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PLEKHB2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Hippo-YAP Cytoskeletal Cytoskeletal | CSRP1, EHD2, FDPS, FLNA, FLNB, MANSC1, MAP1B, MSRB3 +4 more | View in SCUBA |
| Gamma-delta T cells | Post-transcriptional RNA Regulation RNA processing & translation | CCNG1, DHX15, FUBP1, HNRNPA3, IPO7, ITPR2, OSBPL3, SP140 | |
| Macrophages | ER Membrane Homeostasis Housekeeping | ATP6V1A, BNIP2, CANX, CAPZA1, CD164, CMTM6, COPB1, EXOC5 +18 more | View in SCUBA |
About the gene
| Synonyms | EVT2, FLJ20783 |
|---|---|
| Chromosome | 2: 131104847-131353709 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Involved in retrograde transport of recycling endosomes
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.