SLC27A3 — Solute carrier family 27 member 3
SLC27A3 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC27A3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Lymphocyte Homeostatic Regulation Housekeeping | BSG, CTDSP1, FBXW5, HMGN4, IGSF8, IKBKG, LRP10, MFNG +8 more | |
| Lymphatic endothelial | Lymphatic Vascular Stability endothelial development | GJA1, GLT8D2, HIC1, HSD17B12, IGFBP4, KCTD12, MAF, ROBO4 +6 more | View in SCUBA |
| Macrophages | Myeloid Immune Checkpoint Innate immunity | CD276, CLEC12A, ITGAL, LIMK1, SELENON, SORT1, SPINT1 | View in SCUBA |
About the gene
| Synonyms | ACSVL3, FATP3, MGC4365 |
|---|---|
| Chromosome | 1: 153774354-153780157 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Molecular function | Ligase |
| Biological process | Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport |
Function
Mainly functions as an acyl-CoA ligase catalyzing the ATP- dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates. Can mediate the levels of long-chain fatty acids (LCFA) in the cell by facilitating their transport across membranes (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.