SCUBA

LRP10 — LDL receptor related protein 10

LRP10 belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

LRP10's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsB-cell activation
B cell maturation
ADAM19, ARHGAP30, CD164, CD19, CD47, CLN8, CPEB4, ELK3 +15 moreView in SCUBA
EnterocytesInflammatory hypoxic response
Stress
CAPN2, ISG20, MUC13, MXD1, TM4SF20, TMBIM1, VEGFAView in SCUBA
FibroblastsActin-Integrin Adhesion
Migration & adhesion
ACTR2, ACTR3, C5orf24, CAP1, CD151, DEGS1, FERMT2, GNB1 +5 moreView in SCUBA
Gamma-delta T cellsLymphocyte Homeostatic Regulation
Housekeeping
BSG, CTDSP1, FBXW5, HMGN4, IGSF8, IKBKG, MFNG, RASAL3 +8 more
Goblet cellsActin Cytoskeletal Remodeling
Cytoskeletal
ACTN4, ACTR3, BHLHE40, CAP1, FHL2, KCNK1, SDCBP, SLC7A11 +3 moreView in SCUBA
Innate lymphoid cellsNK/ILC1 Identity
Differentiation
ABCA5, ARHGAP15, CD37, CD96, CD99, CTSD, EPC1, GIMAP2 +17 moreView in SCUBA
Mucosal-associated invariant T cellCellular Housekeeping
Housekeeping
ABI3, AP2M1, CD151, CD2, CKLF, DYNLL1, FDFT1, NOP10 +7 more
NeutrophilsMature Neutrophil Identity
Developmental
JAML, LRRK2, MME, MMP25, MSL1, R3HDM4, SELPLG, TLR8 +1 more

About the gene

SynonymsDKFZP564C1940, LRP9, MGC8675, MST087, MSTP087
Chromosome14: 22871740-22881713
Predicted locationMembrane
Essential geneNo
Protein classPredicted membrane proteins
Molecular functionReceptor
Biological processEndocytosis

Function

Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. May be involved in the uptake of lipoprotein APOE in liver (By similarity)

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.