SNRPA1 — Small nuclear ribonucleoprotein polypeptide A'
SNRPA1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SNRPA1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD8⁺ T cells | Mitochondrial Housekeeping Housekeeping | AURKAIP1, CCDC167, ELOC, ITGB1BP1, MRPL57, NDUFB7, PDCD5, RBM17 +2 more | View in SCUBA |
| Gamma-delta T cells | snRNP Splicing RNA processing & translation | CHCHD2, DAZAP1, GAPDH, GIT1, GUK1, HDGF, ILF2, LAMTOR5 +16 more | |
| Macrophages | Replication Chromatin Assembly Cell cycle | ANP32B, CBX3, CDK4, COPS3, DEK, DNMT1, EMC8, EXOSC8 +22 more | View in SCUBA |
| Mucosal-associated invariant T cell | mRNA Decay Program RNA processing & translation | ATP6V0C, BCL7B, BTG1, BTG3, CCDC59, DDIT4, DUSP2, DYNLL2 +13 more |
About the gene
| Synonyms | Lea1, U2A' |
|---|---|
| Chromosome | 15: 101281510-101295282 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Ribonucleoprotein, RNA-binding |
| Biological process | mRNA processing, mRNA splicing |
Function
Involved in pre-mRNA splicing as component of the spliceosome. Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.