SCUBA

NDUFB7 — NADH:ubiquinone oxidoreductase subunit B7

NDUFB7 belongs to a gene co-expression module in 13 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

NDUFB7's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsOxPhos & proteasome
Mitochondrial & OxPhos
CCDC167, CLTA, COX17, COX5A, DBI, FKBP1A, FMNL1, GALM +10 moreView in SCUBA
CD8⁺ T cellsMitochondrial Housekeeping
Housekeeping
AURKAIP1, CCDC167, ELOC, ITGB1BP1, MRPL57, PDCD5, RBM17, SNRPA1 +2 moreView in SCUBA
EndothelialHousekeeping Metabolic
Housekeeping
ANXA5, ATP5MC3, CCT5, COX6B1, CTSL, DCTPP1, ERH, GSTO1 +8 moreView in SCUBA
EnterocytesRespiratory Chain Subunits
Mitochondrial & OxPhos
ATP5F1D, ATP5ME, CHCHD10, COX5A, NDUFB10, PRDX2View in SCUBA
FibroblastsMitochondrial OxPhos
Mitochondrial & OxPhos
ATP5PF, COX6A1, COX6C, GSTP1, MGST3, NDUFA12, NDUFA8, NDUFB10 +6 moreView in SCUBA
Gamma-delta T cellsCytotoxic Effector Actin
cytotoxicity
ARPC2, ARPC5, ATOX1, BRK1, CFL1, CLIC1, CORO1A, DBI +14 more
Goblet cellsElectron Transport Chain
Mitochondrial & OxPhos
ATP5IF1, ATP5ME, COX5B, DCXR, NDUFA2, NDUFA3, NDUFB1, NDUFB10 +5 moreView in SCUBA
Innate lymphoid cellsRNA Splicing Processing
RNA processing & translation
ATP5F1C, CHMP2A, CHMP4A, CYBA, DSTN, DYNC1I2, DYNLRB1, FKBP3 +16 moreView in SCUBA
Lymphatic endothelialMitochondrial OxPhos Complex
Mitochondrial & OxPhos
ARL2, BLOC1S1, CHMP2A, CHURC1, COX5B, DCTN3, FIS1, MRPL43 +5 moreView in SCUBA
MacrophagesOxidative Phosphorylation
Mitochondrial & OxPhos
ATP5F1C, ATP5MC3, ATP5PD, ATP5PO, COX5B, COX6C, LAMTOR2, MICOS10 +7 moreView in SCUBA
Mucosal-associated invariant T cellCyclophilin-Mediated Folding
Housekeeping
B2M, BBLN, BCL7C, C12orf75, CFL1, EDF1, EIF3L, ERH +10 more
Natural Killer cellsGut-Homing NK Maturation
Gut residency
ANXA2, BIN1, DHRS7, HECA, IFI27L2, ITGB7, KLF9, LGALS1 +5 moreView in SCUBA
Smooth muscle cellsOxidative Muscle Metabolism
Mitochondrial & OxPhos
CAV2, COX7A1, CRIP2, FXYD1, HCFC1R1, LGR6, MFGE8, MGST3 +2 moreView in SCUBA

About the gene

SynonymsB18, CI-B18, MGC2480
Chromosome19: 14566078-14572066
Predicted locationIntracellular
Essential geneYes
Protein classEssential proteins, Metabolic proteins, Predicted intracellular proteins
Biological processElectron transport, Respiratory chain, Transport

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.