TBC1D2B — TBC1 domain family member 2B
TBC1D2B belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TBC1D2B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Th17 effector Th17 fate | CD6, CLSTN3, CTDSP1, IL17A, ITPRIPL2, MAP3K4, MPRIP, NFIL3 +6 more | View in SCUBA |
| Fibroblasts | BMP-Wnt Fibroblast Program Developmental | ACP5, BMP5, CTSD, CTXND1, DAAM2, ENPP6, GMFG, TBX2 | View in SCUBA |
| Gamma-delta T cells | Activation Stress Response Stress | ARHGAP9, ARHGEF12, ATF3, ATP6V0A2, GALNT6, GPR18, HIC1, HMCES +12 more | |
| Macrophages | Sphingolipid Membrane Homeostasis Lipid metabolism | ACER3, AGPAT3, ARHGEF11, ATP2A2, C9orf72, CMIP, DMXL2, DOCK8 +12 more | View in SCUBA |
| Mucosal-associated invariant T cell | Tissue Residency Tissue residence | ACSL1, AMFR, CRACDL, DHX36, HES4, IRF8, ITGAE, LZTFL1 +8 more |
About the gene
| Synonyms | KIAA1055 |
|---|---|
| Chromosome | 15: 77984036-78077724 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | GTPase activation |
Function
GTPase-activating protein that plays a role in the early steps of endocytosis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.