TLNRD1 — Talin rod domain containing 1
TLNRD1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TLNRD1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Inflammatory Stress Response Stress | CRK, DLC1, GCLM, IFT20, KRAS, ODC1, SBDS, SERP1 +7 more | View in SCUBA |
| Macrophages | Osmotic Stress Response Stress | ANKRD28, BZW1, CD109, CXCL8, CYB5R4, CYTIP, DUSP4, EMP3 +25 more | View in SCUBA |
| Pericytes | TGF-beta Negative Feedback Inflammatory | CTNND1, DAZAP2, EMP1, KAT6A, KBTBD2, KLF7, MLKL, RCAN1 +6 more | View in SCUBA |
About the gene
| Synonyms | MESDC1, MGC99595 |
|---|---|
| Chromosome | 15: 81000923-81005788 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Actin-binding protein which may have an oncogenic function and regulates cell proliferation, migration and invasion in cancer cells
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.