MAP4 — Microtubule associated protein 4
MAP4 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MAP4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Cytoskeletal Scaffolding Cytoskeletal | ADD1, AGPAT1, ANO6, ARL6IP5, CDC42BPA, CHURC1, DOCK1, ERC1 +6 more | View in SCUBA |
| Fibroblasts | Collagen ECM Production ECM production | AEBP1, ANGPTL2, ANTXR1, CERCAM, CLTC, COL1A1, COL1A2, COL3A1 +12 more | View in SCUBA |
| Gamma-delta T cells | T Cell Calcium-Cytoskeletal T cell maturation | CASP8, CRACR2A, GCNT1, IKZF3, IQGAP1, PRKAR1A, PSEN1, RFFL +5 more | |
| Lymphatic endothelial | Actomyosin Contractility Cytoskeletal | AFAP1L1, C1orf21, COBLL1, EEA1, GNB1, OSBPL8, PPP1R12A, ROCK1 +6 more | View in SCUBA |
| Macrophages | RNA Processing Transport Housekeeping | BCL2, CDYL, CPSF6, DHX15, DHX9, EFR3A, EXOC1, FBXO38 +18 more | View in SCUBA |
| Mucosal-associated invariant T cell | Chromatin Remodeling DNA/chromatin regulation | ANP32E, ARHGAP30, CANX, DCTN1, EPRS1, FLII, HK1, JAK3 +9 more | |
| Natural Killer cells | NK Checkpoint Receptors Immune regulation | CD7, CD96, CRACR2B, DAPK2, ECH1, ECI2, ISYNA1, KIR2DL4 +5 more | View in SCUBA |
About the gene
| Chromosome | 3: 47850690-48089272 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | FDA approved drug targets, Plasma proteins, Predicted intracellular proteins |
Function
Non-neuronal microtubule-associated protein. Promotes microtubule assembly.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.