CDC6 — Cell division cycle 6
CDC6 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CDC6's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Replication Licensing Cell cycle | ASF1B, CDCA5, CDT1, CENPK, CENPU, CLSPN, DNAJC9, FAM111B +5 more | View in SCUBA |
| CD8⁺ T cells | DNA Replication Fork Cell cycle | CDT1, CHAF1A, CTNNAL1, DHFR, DUT, FEN1, LIG1, PCNA +5 more | View in SCUBA |
| Goblet cells | S-phase DNA Replication Cell cycle | ASF1B, BRCA1, CENPU, DHFR, FEN1, MYBL2, PCLAF, TK1 +1 more | View in SCUBA |
| Hematopoietic progenitor cells | Replication Origin Licensing Cell cycle | BRCA1, CLSPN, DTL, FAM111B, MCM10, ORC6, WDR76, XRCC2 |
About the gene
| Synonyms | CDC18L |
|---|---|
| Chromosome | 17: 40287879-40304657 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
| Biological process | Cell cycle, Cell division, DNA replication, Mitosis |
Function
Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.