CNKSR3 — CNKSR family member 3
CNKSR3 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CNKSR3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Endothelial Chemokine Response Chemotaxis | BMP2, CCL2, CEBPB, CEBPD, CXCL1, CXCL2, CXCL3, CXCL8 +14 more | View in SCUBA |
| Enterocytes | Mature colonocyte brush-border Epithelial development | AGMO, ATP8A1, CA3, COBL, EMB, EPB41L3, NGEF, PAG1 +2 more | View in SCUBA |
| Hematopoietic progenitor cells | Mast Cell Differentiation Granulocyte development | ACSL4, ALOX5AP, BACE2, CDK15, FAM81B, FAM83F, FOXJ1, HDC +6 more | |
| Smooth muscle cells | Growth Arrest Stress Stress | BOK, C14orf132, CKAP4, MXRA7, NBPF1, PTGS1, WEE1 | View in SCUBA |
About the gene
| Synonyms | FLJ31349, MAGI1 |
|---|---|
| Chromosome | 6: 154387515-154510685 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Involved in transepithelial sodium transport. Regulates aldosterone-induced and epithelial sodium channel (ENaC)-mediated sodium transport through regulation of ENaC cell surface expression. Acts as a scaffold protein coordinating the assembly of an ENaC- regulatory complex (ERC)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.