APOL2 — Apolipoprotein L2
APOL2 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
APOL2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | IFN-gamma Response Inflammation | APOL6, BATF2, CARD16, CASP1, CD40, CXCL10, CXCL11, CXCL9 +18 more | View in SCUBA |
| Gamma-delta T cells | ER Glycoprotein Quality Control Protein processing & ER | BAG6, CALR, ELP3, GBP1, GBP2, GBP4, HEXB, HSP90B1 +9 more | |
| Glial cells | IFN-gamma Effector Program Inflammation | APOL1, GBP1, IDO1, IFI44L, IL18BP, IL32, LAP3, ODF3B +5 more | View in SCUBA |
| Macrophages | IFN-gamma Response Inflammatory | ANKRD22, ATF5, ATP13A1, CD274, CD300LF, CD40, CD48, CTSH +21 more | View in SCUBA |
| Monocytes | IFN-gamma Response Antiviral | APOL6, CXCL10, ETV7, GBP1, GBP4, GBP5, IFIH1, ISG15 +6 more | View in SCUBA |
| Mucosal-associated invariant T cell | Type I Interferon Inflammation | CHMP5, COMMD8, FBXO6, GBP1, NMI, PARP9, RBCK1, RIGI +9 more |
About the gene
| Synonyms | APOL-II |
|---|---|
| Chromosome | 22: 36226209-36239954 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins |
| Biological process | Lipid transport, Transport |
Function
May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.