ERLEC1 — Endoplasmic reticulum lectin 1
ERLEC1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ERLEC1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Actin Cytoskeletal Remodeling Cytoskeletal | ACTB, ACTG1, ARF1, ARPC5L, CFL1, CYCS, DNAJB11, DNAJC1 +5 more | View in SCUBA |
| Innate lymphoid cells | NK JAK3 Signaling activation | ANKRD44, APLP2, ATP8B4, CALCOCO2, FLOT1, FUT8, FYCO1, HADHB +10 more | View in SCUBA |
| Macrophages | RNA Processing Regulation Housekeeping | ACBD3, AQR, ARCN1, BFAR, BNIP3L, CCNI, CCNK, DIS3 +15 more | View in SCUBA |
About the gene
| Synonyms | C2orf30, CL25084, ERLECTIN, XTP3-B, XTP3TPB |
|---|---|
| Chromosome | 2: 53787009-53833038 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Transporters |
Function
Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non- glycosylated proteins and glycoproteins.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.