ARPC5L — Actin related protein 2/3 complex subunit 5 like
ARPC5L belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARPC5L's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Interferon-stimulated genes Anti-viral | APOBEC3G, ARPC4, BAK1, BST2, DCTN3, ECH1, ETFB, FAM104A +14 more | View in SCUBA |
| Endothelial | Actin Cytoskeletal Remodeling Cytoskeletal | ACTB, ACTG1, ARF1, CFL1, CYCS, DNAJB11, DNAJC1, ERLEC1 +5 more | View in SCUBA |
| Goblet cells | Mitochondrial Biogenesis Mitochondrial & OxPhos | CALM1, EIF5A, LSM7, MRPL17, MRPL20, MRPL41, PFN1, PRELID1 +4 more | View in SCUBA |
| Innate lymphoid cells | Proteasome & TCA Protein processing & ER | ACP1, CAPZA1, CLTA, COPS9, HDAC1, MDH2, NDUFA1, NUDT16L1 +5 more | View in SCUBA |
| Macrophages | Proteasome UPS Housekeeping | ACP1, ATP6V1G1, AURKAIP1, C19orf53, CHMP2A, CIAO2B, CIB1, COPE +31 more | View in SCUBA |
| Natural Killer cells | NK Maturation Program Differentiation | BAALC, CDHR1, EOMES, PDE7A, PDLIM1, S100PBP, SH2D1A, TESC +2 more | View in SCUBA |
| Pericytes | RAS Cytoskeletal Signaling Cytoskeletal | CNDP2, FAM177A1, KLF3, KRAS, LRRFIP1, PEA15, PTPN12, UBE2J1 | View in SCUBA |
About the gene
| Synonyms | ARC16-2, MGC3038 |
|---|---|
| Chromosome | 9: 124862130-124877733 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Actin-binding |
Function
May function as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.