IFFO2 — Intermediate filament family orphan 2
IFFO2 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
IFFO2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Effector activation NFkB TCR/AP1/NFKb pathway | ADAM19, AHR, ARFGAP3, ATF5, BHLHE40, CGAS, DUSP5, ETF1 +23 more | View in SCUBA |
| Gamma-delta T cells | TGF-beta Response Immune regulation | ADGRE5, CD83, CHMP1B, CHST7, DDIT3, DNAAF2, EHD4, FAM43A +15 more | |
| Innate lymphoid cells | AP-1 Transcriptional Activation DNA regulation & transcription | AHNAK, ALYREF, CD81, CDV3, CITED4, ESYT2, ETS1, GNAI2 +28 more | View in SCUBA |
| Mucosal-associated invariant T cell | NF-κB Effector Activation Inflammation | ADGRE5, BCL2A1, CCL20, CCL3, CCL3L3, CCL4, CCL4L2, DUSP10 +10 more | |
| Natural Killer cells | Autophagy-Inflammation Stress Stress | BCL2A1, DDIT3, ICAM1, JMJD6, KLF10, MAP1LC3B, MKNK2, SIK3 +3 more | View in SCUBA |
About the gene
| Chromosome | 1: 18904280-18956676 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.