LUM — Lumican
LUM belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LUM's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Homeostatic Fibroblast Identity ECM production | ADGRL2, C1S, DCN, DKK3, DPYSL2, IL34, IL6ST, PARM1 +6 more | View in SCUBA |
| Pericytes | Stromal ECM Production ECM production | ABCA8, CCL11, CFD, CTSK, DCN, FBLN1, MFAP4, VCAN | View in SCUBA |
| Smooth muscle cells | Matrisome Regulators ECM remodeling | ITM2C, LPP, NBL1, PMP22, S100A13, TCEAL4, TIMP2, TMEM176B +1 more | View in SCUBA |
About the gene
| Synonyms | LDC, SLRR2D |
|---|---|
| Chromosome | 12: 91102629-91111494 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Cancer-related genes, Plasma proteins, Predicted secreted proteins |
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.