PHACTR2 — Phosphatase and actin regulator 2
PHACTR2 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PHACTR2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | mRNA stability regulation Immune regulation | APLP2, ARID5B, CARHSP1, GK, GLCCI1, GRAMD4, HIVEP1, METTL8 +12 more | View in SCUBA |
| Gamma-delta T cells | T Cell Development T cell maturation | ANK3, ATF7IP2, CERK, ERN1, FKBP11, LRIG1, MICAL2, PAG1 +4 more | |
| Innate lymphoid cells | ILC Survival Residency Gut residency | ARID4B, BAZ1A, BCL2A1, CD44, CSF2, CTSH, CXCL8, DUSP4 +25 more | View in SCUBA |
| Macrophages | Mixed Regulatory Signaling Housekeeping | ADAP2, AKAP11, ARHGAP17, ARHGAP27, BLTP2, BLTP3A, C2CD2L, COG2 +30 more | View in SCUBA |
| Neutrophils | Endocytic Vesicular Trafficking Vesicular traficking | CLINT1, DNAJC13, LNPK, PRAM1, PRKAA1, PTPN22, SEC63, VCL |
About the gene
| Synonyms | C6orf56, KIAA0680 |
|---|---|
| Chromosome | 6: 143536845-143831185 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Actin-binding, Protein phosphatase inhibitor |
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.