TINAGL1 — Tubulointerstitial nephritis antigen like 1
TINAGL1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TINAGL1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | ICC niche interactaion Gut motility | ABCC9, ADGRF5, ANO1, CD36, CFHR1, ESAM, FHL5, HOPX +10 more | View in SCUBA |
| Goblet cells | Secreted Antimicrobials Immune function | FAM3D, IFI6, IGFBP2, KLK11, KLK12, NBL1, NOXO1, PCSK1 +6 more | View in SCUBA |
| Pericytes | Pericyte Identity Developmental | ADIRF, CLMN, FRMD3, GPX3, HIGD1B, KLHL23, MAP3K20, PLCE1 | View in SCUBA |
| Smooth muscle cells | Mural/Pericyte Identity Development | C1QTNF1, EBF1, FRMD4A, FRY, ITGA7, LGALSL, LGI4, MCAM +6 more | View in SCUBA |
About the gene
| Synonyms | ARG1, LCN7, LIECG3, P3ECSL, TINAGRP |
|---|---|
| Chromosome | 1: 31576485-31587686 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Enzymes, Predicted intracellular proteins, Predicted secreted proteins |
Function
May be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression in adrenocortical cells. This is a non catalytic peptidase C1 family protein (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.