PRKAR1A — Protein kinase cAMP-dependent type I regulatory subunit alpha
PRKAR1A belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PRKAR1A's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | TCR Activation Signaling TCR/AP1/NFKb pathway | AKNA, ATP6V1A, BCL2L11, KIF20B, LAX1, NAA50, NEDD9, NPC1 +6 more | View in SCUBA |
| Fibroblasts | ER Protein Folding Housekeeping | AHCYL1, CANX, CSNK1A1, HNRNPK, HSP90B1, JAK1, KDELR1, KTN1 +10 more | View in SCUBA |
| Gamma-delta T cells | T Cell Calcium-Cytoskeletal T cell maturation | CASP8, CRACR2A, GCNT1, IKZF3, IQGAP1, MAP4, PSEN1, RFFL +5 more | |
| Innate lymphoid cells | mRNA Stability & Splicing RNA processing & translation | BUD31, EIF4G2, GNAI3, HSPA9, PABPC1, PABPC4, PAIP2, PAPOLA +6 more | View in SCUBA |
| Macrophages | Autophagy Vesicular Trafficking Vesicular traficking | ACTR2, AHCYL1, ALKBH5, BECN1, BICD2, CAP1, CAPRIN1, COLGALT1 +32 more | View in SCUBA |
| Mucosal-associated invariant T cell | Chromatin Remodeling DNA/chromatin regulation | ANP32E, ARHGAP30, CANX, DCTN1, EPRS1, FLII, HK1, JAK3 +9 more |
About the gene
| Synonyms | CNC1, PRKAR1, TSE1 |
|---|---|
| Chromosome | 17: 68511780-68551319 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
Function
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.