GIMAP2 — GTPase, IMAP family member 2
GIMAP2 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GIMAP2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | mRNA Splicing Processing RNA processing | ANXA2R, APOL3, BTN3A1, CCNL1, CHCHD7, CMPK1, DDX5, EIF4A2 +7 more | View in SCUBA |
| Gamma-delta T cells | T Cell Survival T cell maturation | CASP1, CCDC107, CTU1, GEMIN7, GIMAP1, GIMAP4, GIMAP5, GIMAP7 +13 more | |
| Innate lymphoid cells | NK/ILC1 Identity Differentiation | ABCA5, ARHGAP15, CD37, CD96, CD99, CTSD, EPC1, GIMAP6 +17 more | View in SCUBA |
| Macrophages | Innate Antiviral Sensing Innate immunity | ADA2, ADPRH, ALDH9A1, APOBEC3C, BST2, C2, CAT, CD4 +26 more | View in SCUBA |
| Mucosal-associated invariant T cell | Immunoproteasome Activity Inflammation | ABRACL, ARPC5, BANF1, CARD16, CISD3, CYBC1, IMP3, PLAAT4 +4 more |
About the gene
| Synonyms | DKFZp586D0824, HIMAP2, IAN12, IMAP2 |
|---|---|
| Chromosome | 7: 150685697-150693641 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
Function
The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.