CD96 — CD96 molecule

CD96 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

CD96's module in each cell type

Cell type	Module	Shares the module with
CD4⁺ T cells	T cell co-receptors T cell development	AGO4, ARRB2, CAPG, CD200R1, CD40LG, EMB, FKBP11, GAB3 +13 more	View in SCUBA
CD8⁺ T cells	Gut Residence Trm Gut residence	FUT8, ITGAE, METTL8, MYO7A, NAB1, NAP1L4, PAG1, RAB27A +4 more	View in SCUBA
Gamma-delta T cells	Tissue Resident CD103+ Tissue residence	ADRB1, BCAS4, BLMH, CCNJL, CD160, CLIC5, CLNK, DHCR24 +28 more
Innate lymphoid cells	NK/ILC1 Identity Differentiation	ABCA5, ARHGAP15, CD37, CD99, CTSD, EPC1, GIMAP2, GIMAP6 +17 more	View in SCUBA
Mucosal-associated invariant T cell	STAT4 T cell Identity T cell maturation	ATF7IP, CAMK4, CBLB, CELF2, DENND4A, IKZF1, JMJD1C, PIP4K2A +7 more
Natural Killer cells	NK Checkpoint Receptors Immune regulation	CD7, CRACR2B, DAPK2, ECH1, ECI2, ISYNA1, KIR2DL4, MAP4 +5 more	View in SCUBA

About the gene

Synonyms	TACTILE
Chromosome	3: 111292719-111665750
Predicted location	Intracellular, Membrane
Essential gene	No
Protein class	CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Biological process	Cell adhesion

Function

May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.