HSPA4 — Heat shock protein family A (Hsp70) member 4
HSPA4 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
HSPA4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | mRNA splicing RNA processing | ANAPC5, C11orf58, C1orf43, DDX46, DNAJC7, LSM14A, LUC7L3, MRPL47 +8 more | View in SCUBA |
| Gamma-delta T cells | ER/Osmotic Stress Stress | ABHD3, DNAJA4, FKBP4, HIBCH, HSD17B7, HSPB1, MBNL2, MRPL18 +7 more | |
| Innate lymphoid cells | Actin Cytoskeleton Dynamics Cytoskeleton & motility | ACTN4, ALDH9A1, APBB1IP, ARHGAP10, CDC37, CXXC5, FAM136A, FERMT3 +26 more | View in SCUBA |
| Macrophages | Ubiquitin-Proteasome System Housekeeping | ACTR10, ADSS2, ATXN10, CAND1, CYRIB, DKC1, DPM1, EIF4E +18 more | View in SCUBA |
| Natural Killer cells | Inducible HSP70 Stress Stress | BAG3, DNAJB1, FKBP4, HSPA1A, HSPA1B, HSPA6, HSPB1, RHOB +2 more | View in SCUBA |
About the gene
| Synonyms | HS24/P52, HSPH2 |
|---|---|
| Chromosome | 5: 133052013-133106449 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Plasma proteins, Predicted intracellular proteins |
| Biological process | Stress response |
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.