SCUBA

SASH3 — SAM and SH3 domain containing 3

SASH3 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

SASH3's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsEffector Immune Activation
Immune regulation
ABI3, APBB1IP, ASB2, BUB3, CALCOCO2, CASP4, COMMD7, CTSD +7 moreView in SCUBA
Gamma-delta T cellsActin Remodeling
Cytoskeletal
AP1M1, APOBEC3C, ATP5PB, CAP1, CAPN1, CAPZB, DBNL, LSP1 +10 more
Innate lymphoid cellsILC1 Lymphocyte Signaling
Immune regulation
CDIPT, CNPY3, DBNL, ENG, IL16, LIMD2, LSM2, MAPKAPK3 +11 moreView in SCUBA
Mucosal-associated invariant T cellActin Cytoskeletal Remodeling
Cytoskeletal
ANXA6, CAP1, CASP1, CCT5, CCT6A, DEF6, FGD3, GIMAP6 +7 more
Natural Killer cellsNK TGF-β Regulation
Immune regulation
AOAH, CSK, GIMAP5, NCR1, PPP1R18, PTPN6, PYCR2, TGFBR2 +1 moreView in SCUBA

About the gene

Synonyms753P9, CXorf9, HACS2, SH3D6C, SLY
ChromosomeX: 129779949-129795201
Predicted locationIntracellular
Essential geneNo
Protein classDisease related genes, Predicted intracellular proteins

Function

May function as a signaling adapter protein in lymphocytes

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.