PPP1R18 — Protein phosphatase 1 regulatory subunit 18

PPP1R18 belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

PPP1R18's module in each cell type

Cell type	Module	Shares the module with
CD4⁺ T cells	Cytoskeleton & metabolism Cytoskeletal	ATP5F1D, ATP5MC3, ATP6V0E1, BRK1, CAP1, LCK, MYL6, NEDD8 +11 more	View in SCUBA
CD8⁺ T cells	RNA Splicing & ER RNA processing & translation	ARHGDIB, FKBP8, HNRNPA1, MIF, PFN1, PPDPF, SNRPD2, TMED2 +2 more	View in SCUBA
Gamma-delta T cells	Actin Remodeling Cytoskeletal	AP1M1, APOBEC3C, ATP5PB, CAP1, CAPN1, CAPZB, DBNL, LSP1 +10 more
Innate lymphoid cells	ILC1 Actin Motility Cytoskeleton & motility	ACAP1, ARHGDIB, CORO1A, DGCR6L, EVL, GPSM3, HEXA, LCK +14 more	View in SCUBA
Lymphatic endothelial	Integrated Stress Response Stress	ATF4, ATP6V1B2, HNRNPH3, PLEKHO1, TGIF1, UBALD2, ZFAND5	View in SCUBA
Macrophages	Actin Cytoskeleton Organization Cytoskeletal	ACTR3, ARF1, ARHGDIA, ARPC4, CDC42, DERL1, EIF4G2, GARS1 +20 more	View in SCUBA
Mucosal-associated invariant T cell	T cell Homeostasis Housekeeping	ATP5PB, COPZ1, FERMT3, GPS1, HMGN4, ICAM2, LAMTOR2, LCK +14 more
Natural Killer cells	NK TGF-β Regulation Immune regulation	AOAH, CSK, GIMAP5, NCR1, PTPN6, PYCR2, SASH3, TGFBR2 +1 more	View in SCUBA

About the gene

Synonyms	KIAA1949, phostensin
Chromosome	6: 30676389-30687895
Predicted location	Intracellular
Essential gene	No
Protein class	Predicted intracellular proteins
Molecular function	Actin-binding

Function

May target protein phosphatase 1 to F-actin cytoskeleton. May target protein phosphatase 1 to F-actin cytoskeleton

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.