SNRPB2 — Small nuclear ribonucleoprotein polypeptide B2
SNRPB2 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SNRPB2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | mRNA Processing RNA processing | ABI1, AGFG1, CCND3, CD164, CHMP2B, DBF4, GHITM, HNRNPL +9 more | View in SCUBA |
| Gamma-delta T cells | RNA Splicing Nuclear RNA processing & translation | ATRAID, BABAM2, C7orf50, CIB1, CSNK2A1, FUNDC2, GOLGA8A, GOLGA8B +10 more | |
| Glial cells | Proteostasis Stress Response Stress | ATOX1, ATP5MG, ATP6V0E1, C19orf53, C4orf3, COX7B, CYSTM1, GUK1 +7 more | View in SCUBA |
| Innate lymphoid cells | RNA Splicing Processing RNA processing & translation | ATP5F1C, CHMP2A, CHMP4A, CYBA, DSTN, DYNC1I2, DYNLRB1, FKBP3 +16 more | View in SCUBA |
| Macrophages | Proteasome UPS Housekeeping | ATP6V1D, ATP6V1E1, BAX, C1orf43, COX7A2L, DCUN1D5, DNAJC15, DNAJC8 +28 more | View in SCUBA |
| Smooth muscle cells | Sparse Mitoribosomal Housekeeping Housekeeping | CEP63, CIB1, CTNNA1, ERGIC3, FBXO17, LEPROT, MRPL32, MRPL41 +6 more | View in SCUBA |
About the gene
| Synonyms | Msl1, U2B'' |
|---|---|
| Chromosome | 20: 16729961-16742564 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Ribonucleoprotein, RNA-binding |
| Biological process | mRNA processing, mRNA splicing |
Function
Involved in pre-mRNA splicing as component of the spliceosome. Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.