TOB2 — Transducer of ERBB2, 2
TOB2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TOB2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | NK/T Cell Identity T cell maturation | AFTPH, ARHGAP17, ASXL2, ATF7IP, CALCOCO2, CD244, CLK3, GDI1 +24 more | |
| Innate lymphoid cells | mRNA Stability & Splicing RNA processing & translation | BUD31, EIF4G2, GNAI3, HSPA9, PABPC1, PABPC4, PAIP2, PAPOLA +6 more | View in SCUBA |
| Macrophages | Splicing Factor Regulation Housekeeping | ARAP1, CCNL1, CELF1, CLK1, FAM53C, IFRD1, INPPL1, KIDINS220 +12 more | View in SCUBA |
About the gene
| Synonyms | APRO5, bK223H9, TOB4, TOBL, TROB2 |
|---|---|
| Chromosome | 22: 41433494-41446801 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.