TSHZ2 — Teashirt zinc finger homeobox 2
TSHZ2 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TSHZ2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Naive resting T cell T cell development | ACTN1, ADD3, ALKBH7, ANKRD55, ARMH1, CEP170, EDAR, GCNT4 +7 more | View in SCUBA |
| Endothelial | Oxidative Phosphorylation Mitochondrial & OxPhos | ATP5F1D, ATP5MC2, ATP5PO, COX7C, ERP29, HIGD2A, HINT1, IMPDH2 +10 more | View in SCUBA |
| Fibroblasts | ECM Glycan Remodeling ECM remodeling | ATP1B1, CHST11, COL8A2, LIMCH1, MGAT4A, MGAT5, MMP11, MYO7A +3 more | View in SCUBA |
| Mucosal-associated invariant T cell | Naive T cell T cell maturation | AK5, ARID5B, BACH2, CCR7, CSGALNACT1, FHIT, FOXP1, LEF1 +6 more | |
| Pericytes | UC Inflammatory Activation Inflammatory | BDKRB2, CD200, CSF2RB, DUSP23, HLA-DQA1, MEOX1, NR5A2, PCDH17 +3 more | View in SCUBA |
About the gene
| Synonyms | C20orf17, OVC10-2, TSH2, ZABC2, ZNF218 |
|---|---|
| Chromosome | 20: 52972358-53495330 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Transcription factors |
| Molecular function | Developmental protein, DNA-binding, Repressor |
| Biological process | Transcription, Transcription regulation |
Function
Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.