ERP29 — Endoplasmic reticulum protein 29
ERP29 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ERP29's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD8⁺ T cells | Ribosome Biogenesis RNA processing & translation | BTF3, CCND3, EIF3H, EIF3L, FBL, FXYD5, LDHB, LTB +8 more | View in SCUBA |
| Endothelial | Oxidative Phosphorylation Mitochondrial & OxPhos | ATP5F1D, ATP5MC2, ATP5PO, COX7C, HIGD2A, HINT1, IMPDH2, LSM2 +10 more | View in SCUBA |
| Innate lymphoid cells | Proteostasis Stress Response Stress | BUB3, GABARAPL2, HIGD2A, NCOR1, NPM1, POLR1D, SOD1, ST13 +2 more | View in SCUBA |
| Macrophages | Inflammasome Oxidative Stress Inflammatory | ABI3, ADISSP, AKR1A1, ARHGDIB, ARPC1B, ASCL2, BLVRA, C1orf54 +33 more | View in SCUBA |
| Mucosal-associated invariant T cell | Leukocyte Housekeeping Housekeeping | AP2S1, APRT, ATP5MC2, CCDC85B, EIF3G, GABARAPL2, GMFG, HCST +5 more |
About the gene
| Synonyms | C12orf8, ERp28, ERp31, PDI-DB, PDIA9 |
|---|---|
| Chromosome | 12: 112013348-112023449 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
Function
Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.