ZNF706 — Zinc finger protein 706
ZNF706 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ZNF706's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | T cell activation TCR/AP1/NFKb pathway | ANKS1B, ARF6, CCT6A, EHD4, HNRNPM, IRF4, MAP2K3, PFDN2 +3 more | View in SCUBA |
| Innate lymphoid cells | ILC Survival Residency Gut residency | ARID4B, BAZ1A, BCL2A1, CD44, CSF2, CTSH, CXCL8, DUSP4 +25 more | View in SCUBA |
| Lymphatic endothelial | Proteasome Assembly Protein processing & ER | ARPC2, CSTB, DEGS1, GSTO1, MRPL14, PDCD5, POMP, PRELID1 +5 more | View in SCUBA |
| Macrophages | Proteasome UPS Housekeeping | ACP1, ARPC5L, ATP6V1G1, AURKAIP1, C19orf53, CHMP2A, CIAO2B, CIB1 +31 more | View in SCUBA |
About the gene
| Synonyms | HSPC038 |
|---|---|
| Chromosome | 8: 101177878-101206193 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Repressor |
| Biological process | Translation regulation |
Function
Transcription repressor involved in the exit of embryonic stem cells (ESCs) from self-renewal. Acts by repressing expression of KLF4
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.