LSM4 — LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
LSM4 belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LSM4's module in each cell type
About the gene
| Synonyms | YER112W |
|---|---|
| Chromosome | 19: 18306236-18323112 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Molecular function | Ribonucleoprotein, RNA-binding |
| Biological process | mRNA processing, mRNA splicing |
Function
Plays a role in pre-mRNA splicing as component of the U4/U6- U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.