SCUBA

SLC25A37 — Solute carrier family 25 member 37

SLC25A37 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

SLC25A37's module in each cell type

Cell typeModuleShares the module with
EnterocytesMature colonocyte metabolism
Nutrient metabolism
ANXA4, ASS1, ATP1B3, BTNL3, CORO2A, HMCN2, MGAT4A, MOB3B +6 moreView in SCUBA
FibroblastsNFAT-cAMP Signaling
Inflammatory
ACKR3, ADGRE2, ANKRD28, CHSY1, CREM, ELL2, FRMD4A, GPCPD1 +3 moreView in SCUBA
MacrophagesInflammatory Monocyte Activation
Inflammatory
ANPEP, AQP9, CD300E, CD82, CLEC5A, CXXC5, DDX60L, DHRS9 +25 moreView in SCUBA
MonocytesInflammatory Metabolic Reprogramming
Inflammatory
ACTN1, ADAM8, DGAT2, EAF1, GPAT3, MCTP2, PTPN7, SLC2A3View in SCUBA
NeutrophilsBacterial Phagocytosis Program
Phagocytosis
CASP4, CLEC7A, CSF2RB, CSF3R, CYTH4, FCGR2A, LY96, SLC11A1 +1 more

About the gene

SynonymsHT015, MFRN, MFRN1, MSCP
Chromosome8: 23528956-23575463
Predicted locationIntracellular
Essential geneNo
Protein classMetabolic proteins, Predicted intracellular proteins, Transporters
Biological processIon transport, Iron transport, Transport

Function

Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.