TMEM131 — Transmembrane protein 131
TMEM131 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TMEM131's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | B Cell Identity Signaling B cell maturation | ARID4B, ELF1, LYN, PAX5, RHOH, ST8SIA4, UGCG | View in SCUBA |
| Gamma-delta T cells | Transcriptional Repressor Complex DNA/chromatin regulation | BAG1, CAB39, CLEC2B, EBP, FBXO31, GFI1, MAN1A1, MAP2K1 +14 more | |
| Macrophages | Chromatin Epigenetic Regulation Housekeeping | ABHD17B, ANKH, ARHGAP21, CCNH, CTTNBP2NL, DMXL1, EEIG2, ELF2 +21 more | View in SCUBA |
| Mucosal-associated invariant T cell | Lymphocyte Migration migration & adhesion | AP3B1, ATP9B, BIRC6, BTBD9, CEP350, DOCK11, DOCK2, ERBIN +8 more |
About the gene
| Synonyms | CC28, KIAA0257, PRO1048, RW1, YR-23 |
|---|---|
| Chromosome | 2: 97756333-97995948 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
Function
Collagen binding transmembrane protein involved in collagen secretion by recruiting the ER-to-Golgi transport complex TRAPPIII. May play a role in the immune response to viral infection
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.